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M65® ELISA (Prod. No. 10020)
The M65® ELISA is intended for the quantitative detection of Keratin 18 (K18) present in cell culture supernatants, human serum, human plasma or other body fluids after it has been released from dying cells into the extracellular compartment. The M65 ELISA offers the opportunity to quantify total cell death (due to apoptosis and necrosis) of K18 positive (epithelial) cells.
The M65® ELISA when used in combination with the M30 Apoptosense® ELISA (which specifically measures apoptosis) allows to quantify and distinguish different forms of epithelial cell death as both assays are standardized against the identical reference.
» Click here for Product Data Sheet M65® (Classic) ELISA Fact Sheet #10020
» Click here for M65® ELISA (Classic) Instructions for Use (Manual) Prod. No. #10020
Oncology (Cytotoxic & Biologics Drugs)
Relationship Between Changes in Serum Levels of Keratin 18 and Changes in Liver Histology in Children and Adults With Nonalcoholic Fatty Liver Disease. (PUBMED Link, Abstract)
Cell Death Biomarkers as Early Predictors for Hepatic Dysfunction in Patients After Orthotopic Liver Transplantation. (PUBMED LINK Abstract)