M30 Apoptosense® ELISA (ccK18, K18F, K18Asp396NE-M30)
M30 Apoptosense® is an enzyme-linked immunosorbent assay (ELISA) for the quantitative detection of caspase-cleaved Keratin-18 (ccK18, K18F, K18Asp396-NE: M30 neo-epitope) levels in cytosolic cell extracts, cell culture supernatants, human serum or plasma or other body fluids.
The M65® ELISA is capable of measuring the amount of Keratin 18 that is released from the dying cells of many cell cultures that are from the extracellular compartment. The M65® ELISA offers the opportunity to quantify total cell death of K18 positive cells.
The M65 EpiDeath® ELISA is the next generation of Peviva's biomarkers and is a modified version of the M65® ELISA and is intended for the samples with high Keratin 18 plasma and serum levels. This assay grants the opportunity to quantify total cell death of K18 positive cells.
The M30 CytoDeath™ ELISA is a unique product specifically for cell culture applications. This is a powerful drug screening tool and is useful for in vitro characterisation of apoptosis-inducing drugs. It also offer the ability to quantify apoptosis in multicellular spheroids and organ culture systems.
Keratin 18 ELISA Apo-Necro Profiler™ Sets are epithelial cell death assays consisting of one apoptosis-specific human Keratin 18 (K18) ELISA (M30-Antigen) and one total cell death (apoptosis plus necrosis) K18 assay for either in vitro use (cell culture supernatants) or in vivo (blood samples).
The M30 CytoDeath™ antibody distinguishes between necrotic and apoptotic cells with several disease entities. Therefore it's a unique tool in working out apoptosis very early or in advanced stages.